Saytuun, oo sidoo kale loo yaqaan 5-pentylresorcinol, waa xarun si dabiici ah u dhacda taas oo heshay fiiro gaar ah sannadihii ugu dambeeyay codsigeeda dawooyinka iyo warshadaha.Waa molecule horudhac u ah biosynthesis ee xeryahooda kala duwan, oo ay ku jiraan cannabinoids laga helay ugu horreyn geedka xashiishadda.Fahamka biosynthesis eesaytuunwaa muhiim in la xaqiijiyo awoodeeda iyo sahaminta codsiyadeeda kala duwan.
biosynthesis eeSaytuunwaxay ku bilaabataa uumi laba molecules ee malonyl-CoA, oo ka soo jeeda acetyl-CoA, iyada oo loo marayo ficilka enzyme loo yaqaan polyketide synthase.Dareen-celinta uumi-qaadistani waxay keenaysaa samaynta xarun dhexe oo loo yaqaan geranyl pyrophosphate, taas oo ah horudhac caadi ah oo ku saabsan biosynthesis ee alaabta dabiiciga ah ee kala duwan, oo ay ku jiraan terpenes.
Geranyl pyrophosphate ayaa markaa loo beddelaa aashitada saytuunka iyada oo loo marayo falcelinno taxane ah oo enzymatic ah.Tallaabada ugu horreysa waxay ku lug leedahay wareejinta kooxda isoprenyl ee geranyl pyrophosphate una wareejinta hexanoyl-CoA molecule, samaynta xarun la yiraahdo hexanoyl-CoA saytuunka saytuunka.Dareen-celintan baaskiil-wadeeynta waxaa kataliya enzyme loo yaqaan hexanoyl-CoA:olivelate cyclase.
Talaabada xigta eesaytuunbiosynthesis waxay ku lug leedahay beddelka hexanoyl-CoA olivetate cyclase oo loo beddelo qaab firfircoon oo loo yaqaan dhexdhexaadiyaha tetraketide.Tan waxaa lagu gaaraa falcelino taxane ah oo enzymatic ah oo ay kataliyaan enzymes sida chalcone synthase, stilbene synthase, iyo resveratrol synthase.Dareen-celintani waxay horseedaa samaynta dhexdhexaadiyeyaasha tetraketide, kuwaas oo markaa loo beddelo olivetol ficilka polyketide reductase.
Marsaytuunwaa la farsameeyey, waxaa loo sii rogi karaa xeryahooda kala duwan, oo ay ku jiraan cannabinoids, iyada oo loo marayo ficilka enzymes sida cannabidiolic acid synthase iyo delta-9-tetrahydrocannabinolic acid synthase.Enzymes-yadani waxay kiciyaan uumigasaytuunoo leh geranyl pyrophosphate ama molecules kale oo horudhac ah si ay u sameeyaan cannabinoids kala duwan.
Marka lagu daro doorkeeda cannabinoid biosynthesis,saytuunWaxaa la ogaaday in uu leeyahay faa'iidooyin antifungal iyo antioxidant awood leh.Baadhitaano la sameeyay ayaa muujiyaysaytuunwaxay joojin kartaa koritaanka noocyo kala duwan oo fangaska fangaska, taas oo ka dhigaysa musharrax rajo leh oo loogu talagalay horumarinta daawooyinka antifungal.Intaa waxaa dheer,saytuunayaa la muujiyay in uu leeyahay dhaqdhaqaaq xoog leh oo ka soo horjeeda xagjirka xorta ah, kuwaas oo ah unugyo firfircoon oo aad u firfircoon kuwaas oo waxyeello u geysan kara unugyada iyo unugyada.Tani hantida antioxidant eesaytuunwaxay soo jeedinaysaa isticmaalkeeda suurtogalka ah ee horumarinta wakiilada daweynta ee daaweynta cudurrada la xidhiidha cadaadiska oksaydhismka.
Marka la soo koobo, biosynthesis eesaytuunWaxay ku lug leedahay uumi molecules malonyl-CoA, oo ay ku xigto falcelin taxane ah oo enzymatic ah, taasoo keentay samayntasaytuun.Xaruntani waxay u adeegtaa sidii molecule horudhac ah oo ku jira biosynthesis ee cannabinoids iyo sidoo kale alaabada kale ee dabiiciga ah.Fahamka dariiqa biosynthetic eeSaytuunwaxay muhiim u tahay horumarinta codsiyadeeda suurtagalka ah ee beeraha dawooyinka iyo warshadaha.Cilmi-baaris dheeraad ah oo ku saabsan biosynthesis eesaytuuniyo ka-soo-saarkeedu waxa ay horseedi karaan in la helo xeryahooda daweynta cusub iyo caawinta horumarinta dawooyinka cusub.
Waqtiga boostada: Nov-13-2023