Aashitada Obeticholic waxa loo isticmaalaa kaligiis ama daawaynta isku dhafan ee cudur beerka qaarkood (Bilyary cholangitis-PBC)
Magaca Alaabta | Obeticolic acid |
Magaca Kiimikada | 6-Ethylchenodeoxycholic acid |
Magac Kale | 3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic 747 -ECCDA) |
Lambarka CAS | 459789-99-2 |
Qaanuunka molecular | C26H44O4 |
Miisaanka Formula | 420.63 |
Muuqashada | budo cad |
Qiimayn | 99.0% min |
Cufnaanta | 1.091 g/cm3 |
Meesha dhalaalaysa | 108-110 °C |
Barta Karsan | 562.9±25.0 °C |
Xidhmada | 20kg/bac/ durbaan, 25kg/bac/durbaan, ama sida aad u baahan tahay |
Kaydinta | Ku kaydi weelka si adag oo xiran meel qalalan oo qabow.Ha u bandhigin iftiinka qorraxda tooska ah. |
COA & MSDS | La heli karo |
Obeticholic acid waa dihydroxy-5beta-cholanic acid taaso ah chenodeoxycholic acid sido bedel ethyl dheeraad ah oo ah booska 6alpha.Bile acid-synthetic semi-synthetic kaas oo u shaqeeya sidii farnesoid X receptor agonist oo loo isticmaalo daaweynta cholangitis biliary aasaasiga ah.Waxay leedahay door sida farnesoid X reseptor agonist iyo wakiilka hepatoprotective.Waa dihydroxy-5beta-cholanic acid, 3alpha-hydroxy steroid iyo 7alfa-hydroxy steroid.Waxay ka timaadaa chenodeoxycholic acid.
Obeticholic acid (OCA) waa bile acid synthetically modified iyo agonist xoog leh ee farnesoid X nuclear reseptor (FXR) kaas oo loo isticmaalo in lagu daweeyo cudurada beerka oo ay ku jiraan biliary cholangitis aasaasiga ah.
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Waqtiga hogaaminta
≤100kg: saddex maalmood oo shaqo gudahood ka dib markii lacagta la helay.
>100kg: hal todobaad
Tusaale
La heli karo
Xidhmada
20kg/bac/durbaan, 25kg/bac/durbaan
ama sida aad u baahan tahay.
Kaydinta
Ku kaydi weelka si adag oo xiran meel qalalan oo qabow.
Ha u bandhigin iftiinka qorraxda tooska ah.