Chlormadinone acetate (CMA) waa agonist awood leh oo progesterone ah (PR), antagonist qayb ka mid ah androgen receptor (AR) antagonist iyo antagonist glucocorticoid (GR) daciif ah.Chlormadinone waxay ku xidhan tahay PRs, taas oo kicisa muujinta progesterone - hiddo-wadaha jawaab-celinta.
Magaca Alaabta | Chlormadinone acetate |
Magaca Kiimikada | 17a-acetoxy-6-chloro-4,6-uur-uur-3,20-dione |
Magac Kale | Clormadinoneacetate; chloromadinone17-acetate;6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione;17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione,6-Chloro- 6-dehydro-17a-acetoxyprogesterone, Gestafortin,Matrol,Menstridyl,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate;17-alpha-acetoxy-;ChChemicalbooklormadinoneacetate,17 -chloro-4,6-pregnadiene-3,20-dione,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate,6-Chloro-6-dehydro-17α-acetoxyprogesterone, Gestafortin ,Matrolka, Ragga;(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12 ,13,14,15,16,17-dodecahydro-1H-cyclopenta[a] phenanthren-17-ylacetate |
Lambarka CAS | 302-22-7 |
Qaanuunka molecular | C23H29ClO4 |
Miisaanka Formula | 404.93 |
Muuqashada | Budada Crystalline Cad ilaa Jaalle;Aan ur lahayn, dhadhamin |
Qiimayn | 98.0% min |
Meesha dhalaalaysa | 212°C |
Barta Karsan | 512.5±50.0 °C |
Meesha ugu sarreysa ee nuugista | 1.1345 g/cm3 |
Xidhmada | 20kg/bac/ durbaan, 25kg/bac/durbaan, ama sida aad u baahan tahay |
Kaydinta | Ku kaydi weelka si adag oo xiran meel qalalan oo qabow.Ha u bandhigin iftiinka qorraxda tooska ah. |
COA & MSDS | La heli karo |
Codsiga | Ujeeddo cilmi baadhiseed |
TIJAAB | SHURUUDAHA AQBALKA | NATIIJADA |
Aqoonsiga | TLC | Wanagsan |
UV spectrum | Wanagsan | |
IR spectrum | Wanagsan | |
Astaamaha | Budada crystalline cad ama huruud ah | waafaqsan |
barta dhalaalaysa | 211 ~ 215 ℃ | 211 ~ 214 ℃ |
Wareegga indhaha ee gaarka ah | ﹣10° ~﹣14° | ﹣12.5° |
Solubility | si xor ah ugu milmay chloroform, ku milma acetonitrile, wax yar ku milma ethanol iyo ether oo aan si dhab ah biyo ugu milmin. | waafaqsan |
Luminta qalajinta | ≤0.5% | 0.21% |
Hadhaaga dabka | ≤0.1% | 0.04% |
steroids kale | ≤1.0% | 0.59% |
Biraha culus | ≤20pm | Gudub |
Arsenic | ≤2pm | Gudub |
Qiimayn | ≥98.0% | 98.9% |
Xalliyeyaasha haraaga ah (GC) | Acetone ≤5000ppm Methanol≤3000ppm Pyridine≤200ppm | Gudub Gudub Gudub |
Chlormadinone acetate waa progestin iyo daawada antiandrogen kaas oo loo isticmaalo kaniiniyada ilaalinta dhalmada si looga hortago uurka, iyada oo qayb ka ah daaweynta hoormoonka menopausal, daaweynta cudurrada haweenka, iyo daaweynta xaaladaha ku-tiirsanaanta sida qanjidhada qanjirka 'prostate' iyo kansarka qanjirka 'prostate' ragga iyo finan iyo hirsutism dumarka.
Sideen u qaataa Chlormadinone acetate?
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Waqtiga hogaaminta
≤100kg: saddex maalmood oo shaqo gudahood ka dib markii lacagta la helay.
>100kg: hal todobaad
Tusaale
La heli karo
Xidhmada
20kg/bac/durbaan, 25kg/bac/durbaan
ama sida aad u baahan tahay.
Kaydinta
Ku kaydi weelka si adag oo xiran meel qalalan oo qabow.
Ha u bandhigin iftiinka qorraxda tooska ah.